Farhad Heydarian; Fatemeh Behmanesh; Mahshid Goodarzi; Farah Ashrafzadeh; Hasan Rakhshandeh
Volume 16, Issue 3 , September and October 2009, , Pages 121-126
Abstract
Background and Purpose: It seems that during seizures special inflammatory processes remain in the epileptic tissues and can induce still another attack. Based on this hypothesis many studies have been conducted to determine the efficacy of non-steroidal anti-inflammatory drugs on controlling seizures ...
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Background and Purpose: It seems that during seizures special inflammatory processes remain in the epileptic tissues and can induce still another attack. Based on this hypothesis many studies have been conducted to determine the efficacy of non-steroidal anti-inflammatory drugs on controlling seizures and have obtained different results. so we decided to perform this research. Therefore the present research was conducted to investigate the effect of ibuprofen on controlling intractable epileptic attacks in children. Methods and Materials: This quasi-experimental double-blind study was conducted in 2006-2007 on 30 patients (3-13 years old) with intractable epilepsy. The patients were observed for one month; then they were given ibuprofen syrup (30 mg/k/day divided into 3 doses) for two months; taking ibuprofen syrup was paused for one month; placebo was given for two months with a similar dosage. Patients simultaneously received their previous anticonvulsant drugs during the study period. In each stage the frequency duration and probable complications of each attack were recorded. The obtained data were analyzed in SPSS using paired t-test and chi-square. Results: Patients’ mean age and mean seizures onset age were 7.23±3.22 and 2.73±2.43 years respectively. Partial complex epilepsy occurred in 13 cases (43.3%) and 17 patients (56.7%) experienced myoclonic epilepsy. Ibuprofen decreased frequency of attacks in 8 cases (26.7%) and even stopped them in 4 cases. However placebo just decreased attacks in 4 cases (13.3%) but the observed difference was not statistically significant (P=0.434). Conclusion: Based on the findings there was no statistically difference between effects of Ibuprofen and placebo on controlling epileptic attacks.
F HEYDARIAN; A HASHEMZADEH
Volume 12, Issue 4 , January and February 2006, , Pages 42-47
Abstract
Background and Purpose: Etiology of pediatric admission is changing. In this study the most common causes of children’s admission and duration of hospitalization were reviewed. In regard to complications of disorders, the results of this study will promote managing and facilities in pediatric ward.
Methods ...
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Background and Purpose: Etiology of pediatric admission is changing. In this study the most common causes of children’s admission and duration of hospitalization were reviewed. In regard to complications of disorders, the results of this study will promote managing and facilities in pediatric ward.
Methods and materials: Pediatric patients admitted to Qa’em Hospital in Mashad, Iran in one year were studied. After filling out the questionnaires using the patient’s records, relevant data were analyzed in SPSS and Excel using chi-sequence and t-test.
Results: Among 800 admitted fever in 57.8%, convulsion in 41%, cough in 20.9% and dyspnea in 7.3% of cases were chief complains. The most common diagnosis included febrile convulsion (41.4%), pneumonia (13.4%), bronchiolitis (8.6%) and asthma (5%).
Conclusion: The prevalence of pneumonia, acute bronchiolitis and febrile convulsion were more common than world’s statistics. But asthma is lower than other regions. Therefore, attention to infections disease and respiratory system disease in particular is necessary.